1. 1457 BC - Battle of Megiddo: Egyptian forces of Thutmose III defeat a large Canaanite coalition under the King of Kadesh.
2. 1178 BC - A solar eclipse may have marked the return of Odysseus, the legendary king of Ithaca, to his kingdom after the Trojan War.
3. AD 73 - Masada, a Jewish fortress, falls to the Romans after several months of siege, ending the Jewish revolt.
4. 556 - Pelagius I begins his reign as Catholic pope.
5. 1071 - Bari falls to Robert Guiscard's Norman forces, ending Byzantine rule in Italy.
6. 1245 - Franciscan envoys Giovanni da Pian del Carpine and Benedict to Pole depart Lyon on the first Catholic mission to the Mongols.
7. 1346 - The Serbian Empire is proclaimed in Skopje at an Easter assembly, and Stephen Uroš IV Dušan is crowned emperor over much of the Balkans.
8. 1395 - Azzo X d'Este is defeated at the Battle of Portomaggiore by Venetian - Ferranese troops.
9. 1509 - The French army under Louis XII enters the Alps.
10. 1521 - Martin Luther arrives at the Diet of Worms assembly.
11. 1582 - Spanish conquistador Hernando de Lerma founds the settlement of Salta in Argentina.
12. 1632 - Albrecht von Wallenstein is appointed supreme military commander of the Holy Roman Empire.
13. 1705 - Queen Anne of England knights Isaac Newton at Trinity College, Cambridge.
14. 1746 - Battle of Culloden: The Jacobite army of Charles Edward Stuart is defeated by royalist troops under the Duke of Cumberland, the last battle on British soil.
15. 1780 - The University of Münster in North Rhine - Westphalia, Germany is founded.
16. 1787 - The first American comedy, The Contrast, makes its debut in NYC.
17. 1789 - George Washington heads for the first presidential inauguration.
18. 1797 - The Spithead mutiny begins: British Royal Navy sailors protest over living and working conditions and pay near Portsmouth.
19. 1799 - Napoleonic Wars: The Battle of Mount Tabor - Napoleon drives Ottoman Turks across the River Jordan near Acre.
20. 1818 - The Senate ratifies the Rush - Bagot Amendment (unarmed US - Canada border).
21. 1849 - Giacomo Meyerbeer's opera Le Prophète premieres in Paris.
22. 1853 - The first passenger railway opens in India, from Bori Bunder (Bombay) to Thane.
23. 1854 - The steamer Long Beach sinks off Long Beach, NY, with 311 dead.
24. 1854 - San Salvador is destroyed by an earthquake.
25. 1858 - The Wernerian Natural History Society, a former Scottish learned society, is wound up.
26. 1861 - US President Abraham Lincoln outlaws business with Confederate states (US Civil War).
27. 1862 - Slavery is abolished in the District of Columbia.
28. 1865 - Battle of Columbus and West Point, Georgia (Ft Tyler), Union forces win one of the last battles of the US Civil War.
29. 1866 - Nitroglycerine explodes at a Wells Fargo & Co office in San Francisco, shattering glass for half a mile.
30. 1868 - Louisiana voters approve a new constitution.
31. 1869 - Ebenezer Bassett, the first African - American diplomat, begins service as minister to Haiti.
32. 1870 - The Vaudeville Theatre Strand opens in London.
33. 1874 - Dr David Livingstone's body arrives in Southampton.
34. 1881 - In Dodge City, Kansas, Bat Masterson fights his last gun battle.
35. 1883 - Paul Kruger is chosen as president of Transvaal.
36. 1888 - Drentse & Friese peat cutters go on strike in the Netherlands.
37. 1900 - The US Post Office issues the first books of postage stamps.
38. 1903 - A large number of Jews are killed in a pogrom in Kishinev, Russia.
39. 1906 - The 10th Boston Marathon is won by 18 - year - old Tim Ford, the youngest race winner.
40. 1908 - Natural Bridges National Monument is established in Utah.
41. 1912 - Harriet Quimby becomes the first woman to fly across the English Channel.
42. 1913 - Bulgarians and Turks agree to an armistice.
43. 1917 - Vladimir Lenin issues his "April Theses" calling for Soviets to take power during the Russian Revolution.
44. 1918 - The British House of Commons passes a new military service bill, taking men up to 55 years old and extending to Ireland.
45. 1919 - The US proposes that Shandong be jointly administered by five countries.
46. 1921 - The Liberal Freedom League forms in The Hague, Netherlands.
47. 1922 - The Treaty of Rapallo between Germany and the Soviet Union is signed, normalizing diplomatic relations.
48. 1940 - Denmark's National Day.
49. 1941 - The Italian - German Tarigo convoy is attacked and destroyed by British ships.
50. 1943 - Albert Hofmann accidentally discovers the hallucinogenic effects of LSD.